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Vol.52 No.6 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/683

Title: RENAL HISTOLOGY IN TYPE 2 DIABETES MELLITUS : CLINICOPATHOLOGIC CORRELATION IN 301 PATIENTS
Authors: Kanauchi, Masao
Akai, Yasuhiro
Iwano, Masayuki
Shiiki, Hideo
Hashimoto, Toshio
Keywords: diabetic nephropathy
protemurla
renal biopsy
urinary albumin
Issue Date: 31-Dec-2001
Publisher: 奈良医学会
奈良県立医科大学
Citation: Journal of Nara Medical Association Vol.52 No.6 p.219-222
Abstract: Renal pathologic features in type 2 diabetes and their correlation with clinical manifestations are incompletely known. Renal biopsy specimens from 301 patients were analyzed retrospectively. Light microscopic findings were graded by Gellman's criteria for diffuse glomerular lesions, which included 44 cases in grade D0, 81 in D1, 98 in D2, 49 in D3, and 29 in D4. Amounts of albuminuria or proteinuria correlated significantly with the grade of diffuse glomerular lesions, as did serum creatinine concentration. Creatinine clearance decreased significantly with increasing severity of glomerular lesions. This evidence strongly supports a close relationship between structural changes and functional abnormalities in diabetic nephropathy.
URI: http://hdl.handle.net/10564/683
ISSN: 13450069
Appears in Collections:Vol.52 No.6

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