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Vol.52 No.2-3 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/655

Title: ASSESSMENT OF BASILAR ARTERY HEMODYNAMICS IN TYPE 2 DIABETIC PATIENTS WITH NO HISTORY OF CEREBROVASCULAR DISEASE BY USING TRANSCRANIAL DOPPLER ULTRASOUND
Authors: Yamano, Shigeru
Akai, Mayumi
Yamamoto, Yuta
Minami, Shigetoshi
Sasaki, Rie
Nakashima, Takao
Takaoka, Minoru
Yamamoto, Junko
Takeda, Yukiji
Kanauchi, Masao
Hashimoto, Toshio
Keywords: blood flow velocity
Fourier pulsatility index
diabetes mellitus
transcranial Doppler ultrasonography
Issue Date: 28-Jun-2001
Publisher: 奈良医学会
奈良県立医科大学
Citation: Journal of Nara Medical Association Vol.52 No.2-3 p.70-77
Abstract: We compared intracranial hemodynamics in 121 type 2 diabetic patients who had no history of cerebrovascular disease with findings in 123 matched control subjects. Mean blood flow velocity (MFV) and Fourier pulsatility index were determined by using transcranial Doppler ultrasonography (TCD). MFV in the basilar artery was significantly lower in diabetic than in nondiabetic subjects (p<0.01), while Fourier PI of the basilar artery was significantly higher in diabetic than in nondiabetic subjects (p<0.01). In multivariate regression analysis, increased Fourier PI and decreased MFV were associated with higher age, female gender, and longer duration of diabetes. Decreased MFV was also associated with microalbuminuria. These findings demonstrated deterioration of basilar artery hemodynamics in patients with type 2 diabetes who have no stroke history. Additionally, repeated TCD may prove to be useful for monitoring cerebrovascular impairments in these patients.
URI: http://hdl.handle.net/10564/655
ISSN: 13450069
Appears in Collections:Vol.52 No.2-3

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