PRIMARY SYSTEMIC AMYLOIDOSIS PRESENTING WITH SEVERE HYPERLIPIDEMIA : A CASE REPORT

Abstract

Primary systemic amyloidosis with severe hyperlipidemia, suspected to be secondary to hepatic involvement, is described. A 48-year-old man was admitted with pretibial edema and abdominal fullness. Laboratory data showed severe hyperlipidemia with lipoprotein X and nephrotic syndrome. Based on biopsy findings of the kidney and liver, he was diagnosed with primary systemic amyloidosis. Hyperlipidemia in this patient was too severe to result only from nephrotic syndrome. Moreover, with lipoprotein X present, we suggest that hepatic amyloidosis can be a cause of severe hyperlipidemia in primary systemic amyloidosis.