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01221 博士論文(医学) >
2024年度 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/4442
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タイトル: | Multidimensional prediction of continuous positive airway pressure adherence |
その他のタイトル: | CPAPアドヒアランスの多次元的予測 |
著者: | Hamada, Eriko Yamauchi, Motoo Fujita, Yukio Nishijima, Tsuguo Ikegami, Azusa Takaoka, Toshio Shirahama, Ryutaro Strohl, Kingman P. Muro, Shigeo |
キーワード: | Cluster analysis CPAP adherence Obstructive sleep apnea Prediction of CPAP adherence |
発行日: | 2024年10月 |
出版者: | Elsevier |
引用: | Sleep medicine. 2024 Oct, vol.122, p.177-184 |
抄録: | Objective: Continuous positive airway pressure (CPAP) is the standard treatment for obstructive sleep apnea (OSA). Unsatisfactory adherence to CPAP is an important clinical issue to resolve. Cluster analysis is a powerful tool to distinguish subgroups in a multidimensional fashion. This study aimed to investigate the use of cluster analysis for predicting CPAP adherence using clinical polysomnographic (PSG) parameters and patient
characteristics.
Patients/methods: Participants of this multicenter observational study were 1133 patients with OSA who were newly diagnosed and implemented CPAP. Ward’s method of cluster analysis was applied to in-laboratory
diagnostic PSG parameters and patient characteristics. CPAP adherence was assessed during 90- and 365-day periods after CPAP initiation in each cluster. We adopted the Centers for Medicare and Medicaid Services criterion for CPAP adherence, i.e., CPAP use ≥4 h per night for 70 % or more of the observation period. Logistic regression analysis was performed to stratify clusters according to CPAP adherence.
Results: Five clusters were identified through cluster analysis. Clustering was significantly associated with CPAP adherence at 90- and 365-day periods after CPAP initiation. Logistic regression revealed that the cluster with
features including apnea predominant sleep-disordered breathing, high apnea-hypopnea index, and relatively older age demonstrated the highest CPAP adherence.
Conclusion: Cluster analysis revealed hidden connections using patient characteristics and PSG parameters to successfully identify patients more likely to adhere to CPAP for 90 days and up to 365 days. When prescribing
CPAP, it is possible to identify patients with OSA who are more likely to be non-adherent. |
内容記述: | 権利情報:© 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies. |
URI: | http://hdl.handle.net/10564/4442 |
ISSN: | 1878-5506 |
DOI: | https://doi.org/10.1016/j.sleep.2024.08.018 |
学位授与番号: | 24601甲第947号 |
学位授与年月日: | 2025-03-14 |
学位名: | 博士(医学) |
出現コレクション: | 2024年度
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