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01 奈良県立医科大学 >
011 医学部 >
0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.48 No.5 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/395
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Title: | 不明熱と高IgM血症を呈した悪性リンパ腫の1剖検例 |
Other Titles: | AN AUTOPSY CASE OF MALIGNANT LYMPHOMA WITH FEVER OF UNKNOWN ETIOLOGY AND HIGH SERUM LEVEL OF IgM |
Authors: | 高井, 英子 山野, 繁 勝山, 慶之 松田, 尚史 椎木, 英夫 藤井, 謙裕 土肥, 和紘 遠藤, 武弘 小西, 陽一 中村, 忍 |
Keywords: | fever of unknown etiology IgM non-Hodgkin's lymphoma |
Issue Date: | 31-Oct-1997 |
Publisher: | 奈良医学会 |
Citation: | 奈良医学雑誌 Vol.48 No.5 p.300-304 |
Abstract: | We report a case of an 80-year-old man with non-Hodgkin's lymphoma and
high serum level of IgM. He was admitted to our hospital because of fever of unknown
etiology and hoarseness. Seven weeks before the current admission, the patient was
admitted to another hospital because of high fever, cough, and anasarca on January 26, 1994.
High serum level of IgM was detected by immunoelectrophoresis in February 1994.
Laboratory tests on admission revealed leucopenia (2,200/μl), high serum level of LDH
(1,012IU/l) and IgM (1,509mg/dl). An abdominal computed tomographic (CT) scan
revealed hepatosplenomegaly without lymphadenopathy.
The patient was diagnosed as having non-Hodgkin's lymphoma (small lymphocytic +
plasmacytoid) by autopsy. Lymphadenopathy was not detected, but tumor cells were
microscopically detected in jugular, axillary, mediastinal, and adbominal lymphnodes. Also
tumor cells had infiltrated to the liver, kidneys, spleen, and pancreas. Immunohistochemical
staining for anti-IgM, IgG, κ-light chain, and λ-light chain showed positive in lymphoid
cells. We experienced a difficult case to diagnose as malignant lymphoma for lack of
lymphadenopathy. |
URI: | http://hdl.handle.net/10564/395 |
ISSN: | 04695550 13450069 |
Appears in Collections: | Vol.48 No.5
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