DSpace About DSpace Software 日本語
 

GINMU >
01 奈良県立医科大学 >
012 大学院 >
0122 学位請求論文 >
01221 博士論文(医学) >
2016年度 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3319

Title: Higher Cognitive Function in Elderly Individuals with Previous Cataract Surgery: Cross-Sectional Association Independent of Visual Acuity in the HEIJO-KYO Cohort.
Other Titles: 白内障手術既往のある高齢者は視力と独立して高い認知機能を維持する : 平城京コホート研究横断解析
Authors: Miyata, Kimie
Obayashi, Kenji
Saeki, Keigo
Tone, Nobuhiro
Tanaka, Kunihiko
Nishi, Tomo
Morikawa, Masayuki
Kurumatani, Norio
Ogata, Nahoko
Issue Date: Jun-2016
Publisher: Mary Ann Liebert Inc.
Citation: Rejuvenation research Vol.19 No.3 p.239-243 (2016 Jun)
Abstract: Cataract surgery improves visual acuity and drastically increases the capacity for light reception to the retina. Although previous studies suggested that both light exposure and visual acuity were associated with cognitive function, the relationships between cataract surgery, visual acuity, and cognitive function have not been evaluated in large populations. In this cross-sectional study, we measured cognitive function using the Mini-Mental State Examination and best-corrected visual acuity in pseudophakic (previous cataract surgery) and phakic (no previous cataract surgery) elderly individuals. Of 945 participants (mean age 71.7 years), 166 (17.6%) had pseudophakia and 317 (33.5%) had impaired cognitive function (score ≤26). The pseudophakic group showed significantly better visual acuity than the phakic group (p = 0.003) and lower age-adjusted odds ratio (ORs) for cognitive impairment (OR 0.66; p = 0.038). Consistently, in multivariate logistic regression models, after adjusting for confounding factors, including visual acuity and socioeconomic status, ORs for cognitive impairment were significantly lower in the pseudophakic group than in the phakic group (OR 0.64; 95% confidence interval 0.43-0.96; p = 0.031). This association remained significant in sensitivity analysis, excluding participants with low cognitive score ≤23 (n = 36). In conclusion, in a general elderly population, prevalence of cognitive impairment was significantly lower in pseudophakic individuals independently of visual acuity. The association was also independent of several major causes of cognitive impairment such as aging, gender, obesity, socioeconomic status, hypertension, diabetes, sleep disturbances, depressive symptoms, and physical inactivity.
Description: 博士(医学)・甲第666号・平成29年3月15日
© Mary Ann Liebert, Inc.
This is a non-final version of an article published in final form in "http://dx.doi.org/10.1089/rej.2015.1718"
URI: http://hdl.handle.net/10564/3319
ISSN: 15491684
Academic Degrees and number: 24601A666
Degree-granting date: 2017-03-15
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2016年度

Files in This Item:

File Description SizeFormat
01_甲666本文の要旨.pdf甲666本文の要旨146.73 kBAdobe PDFView/Open
02_甲666審査要旨.pdf甲666審査要旨488.2 kBAdobe PDFView/Open
03 甲666本文.pdf甲666本文1.22 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback