エロソール吸入シンチグラフィにおける沈着パターンの検討：第二報 SPECT像とCT像の対比によるhot spot形成機序の解析

Abstract

The superimposed images obtained by the SPECT of aerosol inhalation scintigraphy and chest CT were applied in 7 cases of diffuse panbronchiolitis. Aerosol deposition patterns were examined, and hot spots were compared with bronchial morphological abnormalities. The results were as follows : 1. Nevertheless, aerosol deposition patterns were characterized by defects of the depositions in the outer zone and hot spots in the inner zone, hot spots distributed from the inner zone to the outer zone. 2. Hot spots and bronchial morphological abnormalities were markedly matched in the inner zone ; however, they were mismatched in the outer zone. I concluded that the mechanisms of hot spot formation in the inner zone were different from those in the outer zone.