術前凝固スクリーニング異常より発見され，子宮全摘出術を行った先天性第Ⅴ因子欠乏症の1症例

Abstract

A 46-year-old woman diagnosed as having congenital factor Ⅴ deficiency by preoperative screening underwent hysterectomy under the diagnosis of myoma of the uterus. The minimum value of factor Ⅴ could be maintained at the level of 20% by transfusion of fresh frozen plasma. Hydrothorax and ascites were seen 1 week later, but they disappeared with diuretic administration. Excessive hemorrhage during and after the operation was not observed. The patient's elder brother (54 yeares old), free of hemorrhagic symptoms, was also found to have congenital factor Ⅴ deficiency. There may be some cases which are left undiagnosed. So, attention should be paid to excessive hemorrhage after injury and abnormality in preoperative screening.