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01121 Journal of Nara Medical Association >
Vol.45 No.2 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/1700

Title: 膀胱癌における免疫学的パラメータの変動の検討
Authors: 趙, 順規
大園, 誠一郎
吉井, 将人
妻谷, 憲一
二見, 孝
岩井, 哲郎
百瀬, 均
吉田, 克法
三馬, 省二
平尾, 佳彦
岡島, 英五郎
Keywords: immunological parameter
OKT 4/8 ratio
invasive bladder cancer
biological response modifiers
Issue Date: 30-Apr-1994
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.45 No.2 p.119-124
Abstract: The present investigation was conducted to examine the relationship between immunological parameters and prognosis in cases of invasive bladder cancer. A total of 48 patients were entered into this study. They underwent invasive treatment which may greatly affect host immunity (e. g. radical surgery, radiation therapy and cisplatin based combination chemotherapy). Immunological parameters include peripheral lymphocyte count, IgG, IgA, IgM, C3, C4, IgG-FcR(+)T cell, OKT4/8 ratio and Su-PS skin test ; these were examined before and 1, 3 and 6 months after treatment. Peripheral lymphocyte count in the BRM untreated group showed a significant difference between before and after chemotherapy or surgery. Su-PS skin reaction in the BRM untreated group also showed a significant difference between before and after surgery. There were significant differences in OKT 4/8 ratios between cancer death group and no evidence of disease group. These results suggest that OKT4/8 ratio may reflect the prognosis of patients with invasive bladder cancer. In addition, lymphocyte count and Su-PS skin reaction may be parameters of indication for BRM treatment.
URI: http://hdl.handle.net/10564/1700
ISSN: 04695550
Appears in Collections:Vol.45 No.2

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