血清脂質濃度と脂質関連栄養素摂取量との関連

Abstract

The correlations of the intake of the following nutrients to the serum levels of total cholesterol (TCH), high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol, and triglyceride (TG) were investigated in 249 female subjects (aged 55.3 ± 6.0) who participated in our intervention study aiming at decreasing the TCH: energy, protein, carbohydrate, lipid, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, and cholesterol. Daily intakes of various nutrients were estimated in face-to-face interviews by a dietitian trained for the purpose and also using a food frequency questionnaire with dedicated computer software. The TCH, LDL and TG increased with age, while the serum HDL decreased with age. According to the multiple regression analysis conducted taking the serum lipids as dependent variables and intake of various nutrients, including energy intake and age as independent variables, there were no significant independent variables for HDL or TG, and age alone β=0.15) was significant (p<0.05) for TCH. Intake of saturated fatty acids (β=0.15) was a significant independent variable (p<0.05) in addition to age (β=0.18, p<0.01) for LDL, but the total contribution of the intake of saturated fatty acids was 4% lower. The present study suggests that the intake of fat-related nutrients can hardly be estimated from the serum concentrations of lipids such as TCH.