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021 Journal of Nara Medical Association >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/924
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| Title: | COMPOSITIONAL CHANGES OF THE CORONARY ARTERIES WITH AGING IN JAPANESE, THAI, AND MONKEYS |
| Authors: | Tohno, Yoshiyuki
Tohno, Setsuko |
| Keywords: | coronary artery
atherosclerosis
calcium
phosphorus
aging |
| Issue Date: | 30-Apr-2009 |
| Publisher: | 奈良医学会 |
| Citation: | Journal of Nara Medical Association Vol.60 No.1-2 p.15-25 |
| Abstract: | To examine whether there were differences between different races and
between different species in regard to age-related changes of elements and the
relationships among element contents in the coronary arteries, the authors investigated
the left coronary arteries of Japanese, Thai, and monkeys by direct chemical analysis.
After ordinary dissections at Nara Medical University and Chiang Mai University were
finished, the left coronary arteries were resected from the subjects. The anterior
interventricular branch was used as the left coronary artery. The anterior
interventricular branches were also resected from rhesus and Japanese monkeys bred in
the Primate Research Institute, Kyoto University. After ashing of the arteries with nitric
acid and perchloric acid, the element content was determined by inductively coupled
plasma-atomic emission spectrometry.
In the left coronary arteries of Japanese, the average content of Ca increased
remarkably in subjects in their seventies and thereafter increased in the nineties. In the
left coronary arteries of Thai, the average content of Ca increased progressively from the
forties to the seventies.
The average content of Ca in the seventies was two times higher in the left coronary
arteries of Thai than in those of Japanese. The accumulation of Ca in the left coronary
arteries of Thai occurred at least 10 years earlier in comparison with Japanese. In
contrast, the accumulation of Ca hardly occurred at all in the left coronary arteries of
rhesus and Japanese monkeys at old age. Regarding the relationships among element
contents in the left coronary arteries of Japanese and Thai, significant direct correlations
were found among the contents of Ca, P, Mg, Zn, and Na, whereas significant inverse
correlations were found between S and element contents, such as Ca, P, Mg, Zn, and Na. |
| URI: | http://hdl.handle.net/10564/924 |
| ISSN: | 13450069 |
| Appears in Collections: | 021 Journal of Nara Medical Association
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| 15-25p.COMPOSITIONAL CHANGES OF THE CORONARY ARTERIES WITH AGING IN JAPANESE, THAI, AND MONKEYS.pdf | | 1003Kb | Adobe PDF | View/Open |
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