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GINMU >
03 紀要 >
031 Journal of Nara Medical Association >
Vol.60 No.1-2 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/922
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| Title: | GENETICS OF PARKINSON'S DISEASE |
| Authors: | Asai, Hirohide Hirano, Makito Ueno, Satoshi |
| Keywords: | autosomal dominant Parkinson's disease autosomal recessive Parkinson's disease Lewy body |
| Issue Date: | 30-Apr-2009 |
| Publisher: | 奈良医学会 |
| Citation: | Journal of Nara Medical Association Vol.60 No.1-2 p.1-7 |
| Abstract: | Over the last ten years, several genes for monogenic forms of Parkinson's
disease have been mapped and/or cloned. These genes have been implicated in
proteosomal degradation, the oxidative stress response, and mitochondrial function.
These cellular pathways may play a direct role in the etiology of the common sporadic
form of PD. Further, recent genetic, pathologic, and molecular studies have strengthened
the evidence that there is probably more "cross-talk" between the different pathways than
previously appreciated. In this review, we surnmarize the genetic features of monogenic
forms of PD. |
| URI: | http://hdl.handle.net/10564/922 |
| ISSN: | 13450069 |
| Appears in Collections: | Vol.60 No.1-2
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Files in This Item:
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| 01-07p.GENETICS OF PARKINSON'S DISEASE.pdf | | 744Kb | Adobe PDF | View/Open |
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