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Vol.60 No.1-2 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/922

Authors: Asai, Hirohide
Hirano, Makito
Ueno, Satoshi
Keywords: autosomal dominant Parkinson's disease
autosomal recessive Parkinson's disease
Lewy body
Issue Date: 30-Apr-2009
Publisher: 奈良医学会
Citation: Journal of Nara Medical Association Vol.60 No.1-2 p.1-7
Abstract: Over the last ten years, several genes for monogenic forms of Parkinson's disease have been mapped and/or cloned. These genes have been implicated in proteosomal degradation, the oxidative stress response, and mitochondrial function. These cellular pathways may play a direct role in the etiology of the common sporadic form of PD. Further, recent genetic, pathologic, and molecular studies have strengthened the evidence that there is probably more "cross-talk" between the different pathways than previously appreciated. In this review, we surnmarize the genetic features of monogenic forms of PD.
URI: http://hdl.handle.net/10564/922
ISSN: 13450069
Appears in Collections:Vol.60 No.1-2

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