|
GINMU >
01 学術雑誌論文 >
011 医学科 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/908
|
| Title: | What is the Critical Hyperthermia Target in Cancer Cells? |
| Authors: | Takahashi, Akihisa
Ohnishi, Takeo |
| Keywords: | hyperthermia
cell killing
protein denaturation
γH2AX
double-strand break |
| Issue Date: | 2006 |
| Publisher: | 日本ハイパーサーミア学会 |
| Citation: | 日本ハイパーサーミア学会誌 = Japanese journal of hyperthermic oncology Vol. 22 (2006) , No. 4 pp.229-237 |
| Abstract: | Currently, the molecular mechanisms involved in heat-induced cell killing are not completely understood, although protein denaturation is known to be the major target for hyperthermia in cancer cells. A new hypothesis is described here which proposes that heat-induced cell killing is associated with cellular DNA double-strand break (DSB) formation. This review provides details of this model for hyperthermia cell killing, and a possible mechanism to explain heat-induced DSB formation. |
| Description: | 著作権者：日本ハイパーサーミア学会
日本ハイパーサーミア学会及び著作者の許諾を得て登録 |
| URI: | http://hdl.handle.net/10564/908 |
| ISSN: | 09112529 |
| Appears in Collections: | 011 医学科
|
Files in This Item:
| File |
Description |
Size | Format |
|---|
| Thermal Medicine 2006 22(4) p.229-237（掲載可）.pdf | | 669Kb | Adobe PDF | View/Open |
|
All items in DSpace are protected by copyright, with all rights reserved.
|
