出生当日に発症した発作性上室性頻拍症にATPが有効であった低出生体重児の1例

Abstract

We report a case in which paroxysmal supraventricular tachycardia (PSVT) in a low-birth-weight newborn, due to atrioventricular nodal re-entry, was successfully treated by intravenous bolus injection of adenosine-5'-triphosphate (ATP). The newborn was a male, born after 36 weeks and 1 day of gestation, weighing 2,204g. One hour after birth, he exhibited tachycardia, at 250 to 270 beats/min. A chest radiogragh revealed cardiomegaly, with a cardiothoracic ratio of 71％. Injection of ATP at a dose of O.3mg/kg resulted in complete cessation of PSVT, with temporary suppression of the sinus node and resumption of normal sinus rhythm within 10 seconds after injection. No serious side effects of ATP injection occurred. Oral digoxin treatment was administered for 10 months after ATP injection, to prevent recurrence of tachycardia. The patient is now 3 years and 2 months old, and there has been no recurrence of tachycardia.