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01121 Journal of Nara Medical Association >
Vol.46 No.3 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/825
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Title: | AUDITORY P300 EVENT-RELATED POTENTIALS AND MINI MENTAL STATE EXAMINATION PERFORMANCE IN DEMENTIA ; EFFECTS OF IDEBENONE AND VINPOCETINE |
Authors: | Kishimoto, Toshifumi Hiraoka, Yukie Oribe, Hiroaki Inoue, Makoto Ueda, Atsushi Matsuyama, Mitsuharu Inoue, Yuichiro Itoh, Takashi Yoshitomi, Katsunari Miyagi, Tetsuro Masuda, Nobuaki Tatsuda, Hiroshi Nakanishi, Yasuo Negoro, Hideki Ikawa, Genro |
Keywords: | vascular dementia event-related potentials (ERPs) Idebenone Vinpocetine |
Issue Date: | 30-Jun-1995 |
Publisher: | 奈良医学会 |
Citation: | 奈良医学雑誌 Vol.46 No.3 p.259-266 |
Abstract: | One group of twenty-one demented patients were administered Idebenone
90 mg/day for eight weeks, the other group of thirty-two demented patients were adminis-
tered Idebenone 90 mg/day plus Vinpocetine 15 mg/day for eight weeks. Mini Mental State
Examination (MMSE) was carried out and auditory event-related potentials (ERPs) were
recorded pre-treatment, after four weeks treatment and after eight weeks treatmet.
MMSE performance was significantly improved with treatment in both groups. Central
P300 latency was shortened in the group which was treated with Idebenone and Vinpocetine,
but not in the group which was treated with Idebenone alone. Based on the obtained results,
we were convinced that administration of Idebenone and Vinpocetine was very useful in the
treatment of vascular dementia. |
URI: | http://hdl.handle.net/10564/825 |
ISSN: | 04695550 13450069 |
Appears in Collections: | Vol.46 No.3
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