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Vol.46 No.3 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/825

Title: AUDITORY P300 EVENT-RELATED POTENTIALS AND MINI MENTAL STATE EXAMINATION PERFORMANCE IN DEMENTIA ; EFFECTS OF IDEBENONE AND VINPOCETINE
Authors: Kishimoto, Toshifumi
Hiraoka, Yukie
Oribe, Hiroaki
Inoue, Makoto
Ueda, Atsushi
Matsuyama, Mitsuharu
Inoue, Yuichiro
Itoh, Takashi
Yoshitomi, Katsunari
Miyagi, Tetsuro
Masuda, Nobuaki
Tatsuda, Hiroshi
Nakanishi, Yasuo
Negoro, Hideki
Ikawa, Genro
Keywords: vascular dementia
event-related potentials (ERPs)
Idebenone
Vinpocetine
Issue Date: 30-Jun-1995
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.46 No.3 p.259-266
Abstract: One group of twenty-one demented patients were administered Idebenone 90 mg/day for eight weeks, the other group of thirty-two demented patients were adminis- tered Idebenone 90 mg/day plus Vinpocetine 15 mg/day for eight weeks. Mini Mental State Examination (MMSE) was carried out and auditory event-related potentials (ERPs) were recorded pre-treatment, after four weeks treatment and after eight weeks treatmet. MMSE performance was significantly improved with treatment in both groups. Central P300 latency was shortened in the group which was treated with Idebenone and Vinpocetine, but not in the group which was treated with Idebenone alone. Based on the obtained results, we were convinced that administration of Idebenone and Vinpocetine was very useful in the treatment of vascular dementia.
URI: http://hdl.handle.net/10564/825
ISSN: 04695550
13450069
Appears in Collections:Vol.46 No.3

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