DSpace About DSpace Software 日本語
 

GINMU >
01 奈良県立医科大学 >
011 医学部 >
0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.46 No.3 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/824

Title: DENTATORUBRAL-PALLIDOLUYSIAN ATROPHY (DRPLA) AND MIDLATENCY AUDITORY EVOKED RESPONSES
Authors: Kishimoto, Toshifumi
Higashiura, Naoto
Hiraoka, Yukie
Sakiyama, Shinobu
Kirita, Ikuhiro
Noriyama, Yoshinobu
Itoh, Naoto
Ueda, Atsushi
Oribe, Hiroaki
Ikawa, Genro
Keywords: midlatency auditory evoked responses
DRPLA
molecular diagnosis
P1 abnormality
Issue Date: 30-Jun-1995
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.46 No.3 p.251-258
Abstract: The human 'P1' middle latency evoked potential is postulated to be generat- ed in the thalamus by a cholinergic component of the ascending reticular activating system. To test the midbrain function of dentatorubral-pallidoluysian atrophy (DRPLA), recording of middle latency response to click stimuli were carried out in a DRPLA family which was detected with the aid of molecular diagnosis. Comparisons between the DRPLA members and the normal members indicated normal Pa responses but P1 component is abnormal in DRPLA. This P1 abnormality suggests that the midbrain cholinergic cells in DRPLA may be dysfunctional.
URI: http://hdl.handle.net/10564/824
ISSN: 04695550
13450069
Appears in Collections:Vol.46 No.3

Files in This Item:

File Description SizeFormat
251-258p.DENTATORUBRAL-PALLIDOLUYSIAN_ATROPHY.pdf1.07 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback