恥骨融解を伴った膀胱部非特異的炎症性肉芽腫の一例

Abstract

A case of non-specific inflammatory granuloma of the urinary bladder is reported. A 16-year-old high school student visited our outpatient clinic with the com- plaints of fever and severe perineal discomfort after a 3-week medication. Diagnostic imagings showed a mass formation at the anterior wall of the urinary bladder extending to the surrounding tissue, and an osteolytic change of the pubic bone was recognized. The first two biopsies by a needle and TUR failed to diagnose. A sufficient amount of tissue obtained by an open biopsy finally led to the diagnosis of non-specific inflammatory granulation. The patient received treatment with an antibiotic and 10 mg/day of p. o. predonisolone, which resulted in a 60% reduction of the mass in a week and its complete disappearance in two months. The steroid therapy was terminated after 3 months. We collected only 9 cases of non-specific inflammatory granuloma of the urinary bladder in the Japanese literature. Classifications, diagnosis and treatments of the disease are briefly discussed.