巨大な肝腫大と興味ある腹部CT・MRI画像を呈した原発性アミロイドーシスの1例

Abstract

We report a 51-year-old woman with primary amyloidosis as a case demon- strating the diagnotic usefulness of Magnetic Resonance Imaging (MRI). The patient was admitted to our hospital for further evaluation of nephrotic syndrome. Renal biopsy showed deposition of AL amyloid in the mesangial area and along the capillary wall. An abdominal computed tomographic (CT) scan revealed huge hepatomegaly accompanied by unhomogeneous enhancement. On MRI, T2-weighted image showed significantly reduced intensity in the spleen, while it was mildly reduced in the liver, suggesting massive deposition of amyloid protein in the spleen. The combination of MRI and CT scans is a useful tool for diagnosis of primary amyloidosis.