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03 紀要 >
031 Journal of Nara Medical Association >
Vol.47 No.1 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/704
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| Title: | うつ病性仮性痴呆及び老年期痴呆におけるTRH負荷試験とデキサメサゾン抑制試験に関する検討 |
| Other Titles: | HYPOTHALAMUS-HYPOPHYSIS DYSREGULATION OF DEPRESSIVE PSEUDODEMENTIA AND DEMENTIA IN AGED POPULATION |
| Authors: | 法山, 良信
岸本, 年史
鎌田, 芳郎
東浦, 直人
植田, 敦士
中井, 貴
井村, 徹
田中, 弘
井川, 玄朗
木下, 清子 |
| Keywords: | pseudodementia
TRH stimulation test
dexamethason supression test |
| Issue Date: | 29-Feb-1996 |
| Publisher: | 奈良医学会 |
| Citation: | 奈良医学雑誌 Vol.47 No.1 p.124-128 |
| Abstract: | The aim of this study is to elucidate the difference of hypothalamus-
hypophysis dysregulation between depressive pseudodementia and dementia in aged popula-
tion. Eight patients with pseudodementia due to major depression and eight patients with
dementia of Alzheimer type or cerebral vascular dementia were investigated with the
thyrotropin releasing hormone (TRH) stimulation test and the dexamethason supression
test (DST). Plasma TSH level following injection of TRH and serum cortisol level after
administration of dexamethason were measured. In the demented patients, both ΔTSH and
serum cortisol level after administration of dexamethason were lower than those in the
depressed patients. Since these differences were not significant, further investigation of the
utility of TRH stimulation test and DST is necessary to improve our armamentarium for
diagnosis and treatment of demented states. |
| URI: | http://hdl.handle.net/10564/704 |
| ISSN: | 04695550
13450069 |
| Appears in Collections: | Vol.47 No.1
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| 124-128p.うつ病性仮性痴呆及び老年期痴呆における.pdf | | 572Kb | Adobe PDF | View/Open |
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