慢性副鼻腔炎に対するエアロゾル療法の基礎的研究

Abstract

The clinical use of various aerosol production apparatus for chronic sinusitis was examined. The results are summarized as follows. 1) In aerosol inhalation therapy for chrohic sinusitis the most essential point is that the natural ostia are sufficiently open. 2) Nasal cavities and paranasal sinuses are part of a single organ. Therefore the jet nebulizer and the ultrasonic nebulizer for nasal cavity were also useful for paranasal sinuses when the middle meatus lesions were reversible. 3) The most important factor in promoting aerosol deposition in paranasal sinuses was the application of pressure. Without pressure, none of the nebulizers was able to administer sufficient amounts of therapeutic agents. 4) The ultrasonic nebulizer with pressure added was able to administer the largest amount of agent to the paranasal sinuses. As chronic sinusitis is becoming less severe, aerosol inhalation therapy is becoming more widely used. Even if the middle meatus lesions are irreversible, aerosol inhalation therapy can heal chronic sinusitis when an endonasal operation is employed as well. The correct use of aerosol inhalation therapy should help in the treatment of chronic sinusitis.