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Vol.51 No.5 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/619

Title: 慢性閉塞性肺疾患患者の Health-related Quality of Life の決定要因に関する研究
Other Titles: A STUDY ON THE DETERMINANTS OF HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Authors: 福岡, 篤彦
Keywords: chronic obstructive pulmonary disease
nutrition
health-related quality of life
exercise performance
respiratory function
Issue Date: 31-Oct-2000
Publisher: 奈良医学会
Citation: Journal of Nara Medical Association Vol.51 No.5 p.281-290
Abstract: To investigate the determinants of Health-related Quality of Life (HRQOL) in patients with chronic obstructive pulmonary disease (COPD), I estimated respiratory function, exercise performance and nutritional status, and related them to HRQOL. I examined baseline checking in 55 stable COPD patients cross-sectionally, and then studied interventional randomized trial with PulmocareTM supplementation. I examined HRQOL with the St. George's Respiratory Questionnaire (SGRQ) and Chronic Respiratory Disease Questionnaire (CRQ), respiratorY function, six minutes walking dis- tance test (6MWD), and nutritional status. I estimated fat free mass with bioelectfical impedence analysis and resting energy expenditure with indirect calorimetry technique for parameter of nutritional status. I intervened in ten cases of COPD with fat-based Pulmocare^TM supplement. After three months supplementation I estimated the parameters. SGRQ activity, impacts, and total score were significantly related to 6MWD. % IBW was also related to SGRQ activity, impacts, and total score. Fat free mass/IBW was related to SGRQ impacts score. Pulmocare^TM (fat-based supplement) reduced significantly RQ (p< 0.05) but did not improve respiratory function and HRQOL score. Conclusions : It was suggested that nutritional status is partly related to HRQOL in patients with COPD, and that nutritional supplementation with fat-based supplement decreased RQ.
URI: http://hdl.handle.net/10564/619
ISSN: 13450069
Appears in Collections:Vol.51 No.5

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