血糖コントロール指標としての血糖自己測定(SMBG)の有用性

Abstract

We evaluated the usefulness of self-monitoring of blood glucose (SMBG) as an index of glycemic control in patients with diabetes mellitus. We instructed 59 patients with type 2 diabetes mellitus to measure SMBG levels before the morning and evening meals everyday. SMBG data for 126 continuous days were collected from all patients. We divided the follow-up period (126 days) into 9 sequential periods and calculated the mean SMBG for each period of 14 days. We measured HbAic as an index of long-term glycemic control at the end of follow-up and evaluated the correlation between the value of HbA1c and the mean SMBG of each period in all patients. The mean SMBG data (MS) from 27 to 14 days before the end of follow-up showed the best correlation with the value of HbA1c. MS was 112.2±16.8 mg/dl (mean±SD) in the excellent-control group (HbA1c≦6.0%), 127.6±27.4mg/dl in the good-control group (6.0＜HbA1c≦7.0%), 144.4±30.4 mg/dl in the fair-control group (7.0＜HbA1c≦8.5%), and 179.7±23.6 mg/dl in the poor-control group (HbA1c＞8.5%). These findings indicate that SMBG is useful as an index of glycemic control in patients with diabetes mellitus.