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01121 Journal of Nara Medical Association >
Vol.50 No.4 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/533
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タイトル: | 短期間に急速な直腸浸潤が認められた未治療前立腺癌の1例 |
その他のタイトル: | RAPID RECTAL INVOLVEMENT BY NON-TREATED PROSTATE CANCER : A CASE REPORT |
著者: | 山口, 旭 田中, 宣道![](/dspace/image/metalink/link_ja.gif) 明山, 達哉 上甲, 政徳 三馬, 省二 |
キーワード: | prostate cancer rectal involvement PSA staining |
発行日: | 1999年8月31日 |
出版者: | 奈良医学会 |
引用: | Journal of Nara Medical Association Vol.50 No.4 p.328-332 |
抄録: | A case with non-treated prostate cancer, which showed rapid rectal involve-
ment in 3 months, is reported. A 62-year-old man visited our out-patient clinic for periodic
follow-up studies for urolithiasis in, August 1997. In spite of having no symptoms on
urination, a Tandem-R (RIA) prostatic specific antigen (PSA) level was 5.8 ng/ml.
Although transrectal ultrasonography demonstrated no signs of malignancy, endorectal MR
imaging done in November showed a low intensity area of 15 mm in diameter in the right
peripheral zone of the prostate. Stage T2 prostate cancer was strongly suspected. At the
time of needle biopsy of the prostate done in 3 months, a solid mass was detected on
ultrasonography at the posterior, distal side of the prostate, which was clearly distinguished
from the prostate. The selectively obtained biopsy specimens from the prostate and the
mass were histopathologically diagnosed as poorly differentiated adenocarcinoma. Thick-
ening of the rectal wall was recognized in MR imaging. From the findings of recto-
sigmoidal colonoscopy and immunohistochemical staining with PSA of both biopsy speci-
mens, the rectal mass was judged to be an invasion of prostate cancer. With a combination
therapy with maximum androgen blockade and radiation, the tumor was reduced in size and
PSA level decreased from 73 ng/ml at the therapy initiation to 0.3 ng/ml. Although
prostate cancer, in general, shows slow growth, a prompt diagnosis might be required, even
when early prostate cancer is suspected. |
URI: | http://hdl.handle.net/10564/533 |
ISSN: | 13450069 |
出現コレクション: | Vol.50 No.4
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