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Vol.50 No.2 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/508
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Title: | インスリン依存型糖尿病を高齢で発症したⅢA型多腺性自己免疫疾患の1例 |
Other Titles: | A CASE OF POLYGLANDULAR AUTOIMMUNE DISEASE TYPE ⅢA WITH ELDERLY ONSET OF INSULIN-DEPENDENT DIABETES MELLITUS |
Authors: | 大江, 厚 西浦, 公章 川野, 貴弘 金内, 雅夫 土肥, 和紘 |
Keywords: | chronic thyroiditis elderly HLA IDDM polyglandular autoimmune disease |
Issue Date: | 30-Apr-1999 |
Publisher: | 奈良医学会 |
Citation: | Journal of Nara Medical Association Vol.50 No.2 p.155-158 |
Abstract: | We report a rare case of insulin-dependent diabetes mellitus (IDDM) with
chronic thyroiditis with elderly onset in a 72-year-old woman. Chronic thyroiditis was
pointed out when she was 68 years old, and she was admitted to our hbspital because of
hyperglycemia following a cold in February of 1998. Laboratory data on admission were
as follows : fasting blood glucose, 417 mg/dl ; HbA₁🇨, 11.3% ; and glycoalbumin, 43.1%.
High titer of anti-thyroglobulin antibody (60.6 U/ml) and anti-thyroid peroxydase anti-
body (over 30.0 U/ml) was observed. Both anti-glutamic acid decarboxylase (GAD)
antibody and islet cell antibody (ICA) were negative. She was diagnosed as having IDDM
because urinary CPR was 4.1 μg/day, and insulin secretion was not induced with glucagon
loading test. She was positive for HLA-A 24 and DR 9 which are typically present in IDDM
patients. Polyglandular autoimmune disease is known to be a multiple endocrine gland
disorder which is induced by autoimmune pathogenesis. This case is included in type ⅢA
polyglandular autoimmune disease. It has been also reported that DR 9 was increased in
type ⅢA polyglandular autoimmune disease. |
URI: | http://hdl.handle.net/10564/508 |
ISSN: | 13450069 |
Appears in Collections: | Vol.50 No.2
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