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031 Journal of Nara Medical Association >
Vol.50 No.2 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/507
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| Title: | A CASE OF BILATERAL HIPPOCAMPAL ATROPHY AND CORTICAL DISTURBANCE OF THE BRAIN AFTER CARDIOPULMONARY RESUSCITATION |
| Authors: | Imanishi, Masami Tabuse, Hisayuki Miyamoto, Seiji Sakaki, Toshisuke Iwasaki, Satoru |
| Keywords: | hippocampus thoracic pump theory cardiopulmonary resuscitation cardiopul-monary arrest |
| Issue Date: | 30-Apr-1999 |
| Publisher: | 奈良医学会 |
| Citation: | Journal of Nara Medical Association Vol.50 No.2 p.149-154 |
| Abstract: | The brain is the most vulnerable organ to ischemia, and the basal ganglia,
cerebral cortex, hippocampus, and cerebellum are the areas most vulnerable to whole brain
ischemia due to sudden cardiopulmonary arrest. Moreover, delayed neuronal death has
been reported to occur in the hippocampus. We report here a case of a 50-year-old man,
who was transferred to our department in sudden cardiopulmonary arrest caused by acute
heart failure hypertrophic cardiomyopathy. He received cardiopulmonary resuscitation,
and spontaneous circulation was restored. However, he fell into a persistent vegetative
state. Disturbance of the cerebral cortex and atrophy of the hippocampus bilaterally were
observed on MR imaging. Hypoperfusion in the cerebral cortex was observed on SPECT.
The atrophy of the hippocampus bilaterally was believed to be caused by delayed neuronal
death after whole brain ischemia. We consider that the comprehensive disturbance of the
cerebral cortex was caused not only by the whole brain ischemia but also by disturbance of
the intracranial venous circulation due to chest compression and increased intracranial
pressure (thoracic pump theory). |
| URI: | http://hdl.handle.net/10564/507 |
| ISSN: | 13450069 |
| Appears in Collections: | Vol.50 No.2
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Files in This Item:
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| 149-154p.A CASE OF BILATERAL HIPPOCAMPAL ATROPHY.pdf | | 2037Kb | Adobe PDF | View/Open |
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