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01121 Journal of Nara Medical Association >
Vol.50 No.1 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/490
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タイトル: | 地域における食事指導の血清総コレステロールに対する効果に関する介入研究 |
その他のタイトル: | AN INTERVENTION STUDY OF THE EFFECT OF CHOLESTEROL-LOWERING DIETARY COUNSELING ON LEVELS OF SERUM LIPIDS |
著者: | 鄭, 燕 |
キーワード: | dietary cholesterol serum cholesterol dietary counseling intervention study |
発行日: | 1999年2月28日 |
出版者: | 奈良医学会 |
引用: | Journal of Nara Medical Association Vol.50 No.1 p.19-32 |
抄録: | To determine the effect of cholesterol-lowering dietary counseling on levels
of serum lipids, a 48-week randomized intervention study was conducted between June 1996
and May 1997 in Nara. A total of 70 Japanese women aged 40-64 years, who had 181-294
mg/dl serum total cholesterol levels but did not receive cholesterol-lowering drug treat-
ment, were randomly assigned to two groups (first intervention group, 35 subjects and
second intervention group, 35 subjects) to receive a 24-week intervention in rotation. The
intervention program included three 40-minute cholesterol-lowering dietary counseling
sessions, and three 2 and a half-hour lectures related to diet and cholesterol. Changes in
dietary intakes and serum lipid levels by the intervention were examined by the paired t-
test, and factors that relate to changes in serum lipid levels were analyzed using the
stepwise multiple regression. After the interventions, significant reductions in intakes of
dietary cholesterol, energy and fat were observed in the two intervention groups. During
the same periods, serum total cholesterol levels decreased significantly by 4% for both
groups, from 238.3 mg/dl to 227.9 mg/dl in the first intervention group, and from 237.9 mg
/dl to 228.4 mg/dl in the second intervention group, and these changes were found to be
related with reductions of dietary cholesterol intakes. Serum HDL cholesterol levels
increased significantly in the two groups during the first 24-week period (June 1996-
December 1996), but no significant relationship between changes in dietary intakes and
serum HDL cholesterol change was observed. Significant reduction of serum triglyceride
level was observed only in the first intervention group after the dietary counseling, and this
change was shown to be associated with reduction of energy percentages of fat intake. The
results indicated that the 24-week cholesterol-lowering dietary intervention program was
effective for reducing serum total cholesterol, but its influence on levels of serum HDL
cholesterol and triglyceride should be further investigated. |
URI: | http://hdl.handle.net/10564/490 |
ISSN: | 13450069 |
出現コレクション: | Vol.50 No.1
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