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GINMU >
03 紀要 >
031 Journal of Nara Medical Association >
Vol.49 No.1 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/425
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| Title: | A CASE OF CUSHING'S SYNDROME ASSOCIATED WITH ISOLATED ADRENOCORTICOTROPIN (ACTH) DEFICIENCY AFTER THE REMOVAL OF CORTISOL-PRODUCING ADRENAL ADENOMA |
| Authors: | Okamoto, Shingo
Umemoto, Norie
Nakatani, Yoshihiro
Hosokawa, Akiko
Izumi, Yukiko
Nishiyama, Toshimasa
Sakamoto, Takemi
Kuriyama, Shigeki
Tsumatani, Kenichi
Hirao, Yoshmiko
Fukui, Hiroshi |
| Keywords: | Isolated adrenocorticotropin deficiency
Isolated ACTH deficiency
Cushing's syndrome pituitary autoantibody |
| Issue Date: | 28-Feb-1998 |
| Publisher: | 奈良医学会 |
| Citation: | 奈良医学雑誌 Vol.49 No.1 p.64-73 |
| Abstract: | A 45-yr-old woman with Cushing's syndrome who could not be withdrawn
from postoperative hydrocortisone supplement for over 3 years after the removal of an
adrenocortical adenoma is presented. This was diagnosed as associating with isolated
ACTH deficiency. She had suffered from persistent severe general fatigure since 5 years
prior. However, after 2 years, obesity, hypertension and moon face developed, while the
malaise improved. She was then diagnosed as having Cushing's syndrome and underwent
the extirpation of right adrenal adenoma. The dosage of supplementary hydrocortisone
was gradually reduced after surgery. However the hydrocortisone dose could not be
reduced lower than 10mg/day after several trials of dose reduction as severe general
fatigue would ensue. The pituitary function tests at postoperative 2 years and a half-year,
revealed an association of isolated ACTH deficiency. It was unknown whether the isolated
ACTH deficiency arose before or after the surgery.
In the present report, we discuss the association of isolated ACTH deficiency and
Cushing's. syndrome. |
| URI: | http://hdl.handle.net/10564/425 |
| ISSN: | 04695550
13450069 |
| Appears in Collections: | Vol.49 No.1
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| 64-73p.A CASE OF CUSHING'S SYNDROME ASSOCIATED WITH ISOLATED.pdf | | 6550Kb | Adobe PDF | View/Open |
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