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Vol.49 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/425

Title: A CASE OF CUSHING'S SYNDROME ASSOCIATED WITH ISOLATED ADRENOCORTICOTROPIN (ACTH) DEFICIENCY AFTER THE REMOVAL OF CORTISOL-PRODUCING ADRENAL ADENOMA
Authors: Okamoto, Shingo
Umemoto, Norie
Nakatani, Yoshihiro
Hosokawa, Akiko
Izumi, Yukiko
Nishiyama, Toshimasa
Sakamoto, Takemi
Kuriyama, Shigeki
Tsumatani, Kenichi
Hirao, Yoshihiko
Fukui, Hiroshi
Keywords: Isolated adrenocorticotropin deficiency
Isolated ACTH deficiency
Cushing's syndrome pituitary autoantibody
Issue Date: 28-Feb-1998
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.49 No.1 p.64-73
Abstract: A 45-yr-old woman with Cushing's syndrome who could not be withdrawn from postoperative hydrocortisone supplement for over 3 years after the removal of an adrenocortical adenoma is presented. This was diagnosed as associating with isolated ACTH deficiency. She had suffered from persistent severe general fatigure since 5 years prior. However, after 2 years, obesity, hypertension and moon face developed, while the malaise improved. She was then diagnosed as having Cushing's syndrome and underwent the extirpation of right adrenal adenoma. The dosage of supplementary hydrocortisone was gradually reduced after surgery. However the hydrocortisone dose could not be reduced lower than 10mg/day after several trials of dose reduction as severe general fatigue would ensue. The pituitary function tests at postoperative 2 years and a half-year, revealed an association of isolated ACTH deficiency. It was unknown whether the isolated ACTH deficiency arose before or after the surgery. In the present report, we discuss the association of isolated ACTH deficiency and Cushing's. syndrome.
URI: http://hdl.handle.net/10564/425
ISSN: 04695550
13450069
Appears in Collections:Vol.49 No.1

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