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Vol.49 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/424

Title: A CASE OF TYPE II POLYGLANDULAR AUTOIMMUNE DISEASE (SCHMIDT'S SYNDROME) ASSOCIATED WITH A MYOPATHY OF UNKNOWN ETIOLOGY
Authors: Okamoto, Shingo
Umemoto, Norie
Kumata, Keiichi
Murata, Kenya
Izumi, Yukiko
Nishiyama, Toshimasa
Sakamoto, Takemi
Kuriyama, Shigeki
Fukui, Hiroshi
Keywords: Schmidt's syndrome
polyglandular autoimmune disease
Addison's disease
myopathy
Issue Date: 28-Feb-1998
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.49 No.1 p.57-63
Abstract: A 44-year-old female with Schmidt's syndrome associated with a myopathy of unknown etiology is reported. The myopathy, characterized by general muscle weakness and extensive atrophy and loss of muscle fibers, developed since the age of 23 y and progressed. The myopathy could not be diagnosed by immuno-histochemistry nor ser- ological examination. Skin pigmentation developed since 40 y. At 44 y, she was diagnosed with Schmidt's syndrome due to the association of autoimmune Addison's disease and Hashimoto's disease. Although the supplemental therapy of hydrocortisone and thyroxin improved adrenal insufficiency and hypothyroidism, the therapy could not improve the muscle weakness of the myopathy. This is the first case of Schmidt's syndrome with a myopathy of unknown etiology like this case.
URI: http://hdl.handle.net/10564/424
ISSN: 04695550
13450069
Appears in Collections:Vol.49 No.1

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