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Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/4105

Title: Factors associated with the increased risk of atlantoaxial osteoarthritis: a retrospective study
Other Titles: 外側環軸関節の関節症性変化のリスク増加に関連する要因; 後ろ向き研究
Authors: Suga, Yuma
Shigematsu, Hideki
Tanaka, Masato
Okuda, Akinori
Kawasaki, Sachiko
Yamamoto, Yusuke
Ikejiri, Masaki
Asai, Hideki
Fukushima, Hidetada
Tanaka, Yasuhito
Keywords: Neck pain
Suboccipital headaches
Atlantoaxial osteoarthritis
Atlantodens joint
Calcification
Transverse ligament
Issue Date: Dec-2022
Publisher: Springer
Citation: European spine journal Vol.31 No.12 p.3418-3425 (2022 Dec)
Abstract: Purpose Atlantodens osteoarthritis and atlantoaxial osteoarthritis cause neck pain and suboccipital headaches. Currently, knowledge on the risk factors for atlantoaxial osteoarthritis is lacking. This study aimed to investigate the factors related to the increased risk of atlantoaxial osteoarthritis. Methods We analyzed computed tomography (CT) images of the upper cervical spine of 1266 adult trauma patients for whom upper cervical spine CT was performed at our hospital between 2014 and 2019. The degree of atlantoaxial osteoarthritis was quantified as none-to-mild (not having osteoarthritis) or moderateto- severe (having osteoarthritis). Risk factors associated with atlantoaxial osteoarthritis were identified using univariate and multivariable logistic regression analyses. Results The study group included 69.4% men, and the overall average age of the study population was 54.9 ± 20.4 years. The following factors were independently and significantly associated with atlantoaxial osteoarthritis in the multivariable logistic regression analysis: age in the sixth decade or older (odds ratio [OR], 20.5; 95% confidence interval [CI], 6.2‒67.2, p < 0.001), having calcific synovitis (OR, 4.9; 95% CI, 2.4‒9.9, p < 0.001), women sex (OR, 3.3; 95% CI, 1.9‒5.7, p = 0.002), and not having atlantodens osteoarthritis (OR, 2.1; 95% CI, 1.2‒3.8, p = 0.014). Conclusion In the multivariable logistic regression analysis, age in the sixth decade or older, calcification of the transverse ligament, being women, and not having atlantodens osteoarthritis were found to be significantly associated with atlantoaxial osteoarthritis. Delayed diagnosis and treatment can be avoided by focusing on these risk factors.
Description: 博士(医学)・甲第873号・令和5年3月15日
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00586-022-07414-5
URI: http://hdl.handle.net/10564/4105
ISSN: 09406719
DOI: https://doi.org/10.1007/s00586-022-07414-5
Academic Degrees and number: 24601甲第873号
Degree-granting date: 2023-03-15
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2022年度

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