DSpace About DSpace Software 日本語
 

GINMU >
01 奈良県立医科大学 >
012 大学院 >
0122 学位請求論文 >
01221 博士論文(医学) >
2020年度 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3783

Title: A Comparison Between Plastic and Metallic Biliary Stent Placement in Patients Receiving Preoperative Neoadjuvant Chemoradiotherapy for Resectable Pancreatic Cancer.
Other Titles: 切除可能膵癌に対する術前化学放射線療法における胆道プラスチックステント及びメタルステントの比較
Authors: Nakamura, Kota
Sho, Masayuki
Akahori, Takahiro
Nagai, Minako
Nishiwada, Satoshi
Nakagawa, Kenji
Tanaka, Toshihiro
Kichikawa, Kimihiko
Tamamoto, Tetsuro
Hasegawa, Masatoshi
Mitoro, Akira
Yoshiji, Hitoshi
Ikeda, Naoya
Issue Date: Feb-2019
Publisher: Springer Nature
Citation: World journal of surgery Vol.43 No.2 p.642-648 (2019 Feb)
Abstract: Background: The optimal stent type in patients receiving preoperative neoadjuvant chemoradiotherapy (NACRT) is uncertain. The present study aimed to compare the clinical effectiveness of biliary metallic stent (MS) and plastic stent (PS) in patients undergoing preoperative NACRT for resectable pancreatic cancer. Methods: This retrospective study included 43 patients who required either biliary MS or PS before initiating NACRT for resectable or borderline resectable pancreatic head cancer. Seventeen patients had MS (MS group), while 23 patients had PS (PS group). All patients received preoperative NACRT, including gemcitabine and concomitant three-dimensional radiation of 54 Gy, and underwent pancreatectomy. Stent patency, surgery postponement, postoperative outcomes, and cost-effectiveness were compared between these groups. Results: There were no significant differences in baseline demographic or tumor characteristics between the groups. Stent patency was significantly longer in the MS group than in the PS group (p = 0.042). There were no differences in time to surgery, intraoperative characteristics, surgical complications, margin positivity, and pathological response between the groups. Furthermore, the medical cost of maintenance of biliary drainage during NACRT was similar between the groups. Conclusions: MS placement compared to PS in patients receiving preoperative NACRT provided no significant benefits during the postoperative course of pancreatectomy. However, MS placement was associated with long stent patency while showing no economic disadvantage. Therefore, MS placement may be recommended in patients receiving preoperative NACRT for resectable pancreatic cancer.
Description: 博士(医学)・乙第1467号・令和2年9月30日
© Société Internationale de Chirurgie 2018
This is a post-peer-review, pre-copyedit version of an article published in World journal of surgery. The final authenticated version is available online at: https://doi.org/10.1007/s00268-018-4820-6.
URI: http://hdl.handle.net/10564/3783
ISSN: 03642313
DOI: https://doi.org/10.1007/s00268-018-4820-6
Academic Degrees and number: 24601B1467
Degree-granting date: 2020-09-30
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2020年度

Files in This Item:

File Description SizeFormat
01乙1467本文の要旨.pdf乙1467本文の要旨1.5 MBAdobe PDFView/Open
02乙1467審査要旨.pdf乙1467審査要旨332.49 kBAdobe PDFView/Open
03乙1467本文.pdf乙1467本文3.78 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback