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01121 Journal of Nara Medical Association >
Vol.48 No.4 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/378

Title: X線学的に1年以上遡及的経過観察が可能であった大腸癌症例の検討
Authors: 畑, 倫明
藤井, 久男
石川, 博文
森田, 敏裕
寺内, 誠司
榎本, 泰三
中野, 博重
吉川, 周作
稲次, 直樹
Keywords: colorectal cancer
doubling time
natural history
Issue Date: 31-Aug-1997
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.48 No.4 p.194-199
Abstract: We report eleven cases overlooked in the initial barium enema. Nine of them had advanced colorectal cancers and two had early colorectal cancers at the time of resection. Initial images of nine advanced colorectal cancers were all sessile tumors and those of two early colorectal cancers were pedunculated or subpedunculated form. Thus, most advanced colorectal cancers may originate from sessile tumor. We also calculate doubling time (DT) of the tumors, radiologically. Average DT of nine advanced cancers is 10.0 months and that of two early cancers is 48.5 months. DT of the advanced cancers is significantly shorter than DT of the early cancers. Considering this fact, DT of the cancers may be shorter when they grow. On the other hand, we discuss DT of the advanced cancers focusing on the duration from the initial examination to the operation (described as "duration" hereinafter). When the duration becomes longer, it may include the period of the early stage of the cancer, in which DT of the tumor is considered long. Therefore, DT may express differences depending on the duration. In our cases, three advanced tumors with durations of less than two years show shorter DT (average 4.8 months) than the other advanced tumors. Thus, if DT is shortening with the cancers' growth, actual DT of advanced cancers might be shorter than calculated DT. With the above-mentioned assump- tion, we should understand that DT of a recurrent cancer after operation might be getting shorter than that of an original tumor before operation.
URI: http://hdl.handle.net/10564/378
ISSN: 04695550
Appears in Collections:Vol.48 No.4

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