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0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.71 No.1,2,3 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3773

Title: がん性サルコペニアに対する栄養介入
Other Titles: Nutritional intervention against cancer-derived sarcopenia.
Authors: 森, 拓也
川原, 勲
額賀, 翔太
宮川, 良博
後藤, 桂
大森, 斉
國安, 弘基
Keywords: 悪液質
Issue Date: 30-Jun-2020
Publisher: 奈良医学会
Citation: Journal of Nara Medical Association Vol.71 No.1,2,3 p.01-05 (2020.06)
Abstract: Most patients with advanced cancer develop skeletal muscle atrophy called sarcopenia, which reduces treatment tolerance and social activity and worsens the prognosis. Glucose suppresses skeletal muscle atrophy in cancer-bearing mice, while promoting cancer growth. In contrast, medium-chain fatty acids reduce skeletal muscle atrophy and suppress cancer growth. Simultaneous administration of glucose and medium-chain fatty acids suppresses skeletal muscle atrophy and eliminates the tumor growth seen with glucose. Based on these findings, dietary intervention using a combination of glucose and medium-chain fatty acids is expected to be effective in suppressing sarcopema in cancer patients.
URI: http://hdl.handle.net/10564/3773
Appears in Collections:Vol.71 No.1,2,3

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