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Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3755

Title: Accuracy of magnetic resonance imaging in predicting dentate line invasion in low rectal cancer.
Other Titles: 下部直腸癌におけるMRIを用いた歯状線浸潤の診断精度
Authors: Tatsumoto, Shota
Itoh, Takahiro
Takahama, Junko
Marugami, Nagaaki
Minamiguchi, Kiyoyuki
Tanaka, Toshihiro
Koyama, Fumikazu
Morita, Kohei
Kichikawa, Kimihiko
Keywords: Anal canal
Dentate line
Magnetic resonance imaging
Rectal cancer
Rectum
Issue Date: Jun-2020
Publisher: Springer
Citation: Japanese journal of radiology Vol.38 No.6 p.539-546 (2020 Jun)
Abstract: Purpose: To retrospectively assess the accuracy of magnetic resonance imaging (MRI) in predicting dentate line invasion in low rectal cancer. Materials and methods: Eighty-one patients with primary rectal cancer were assessed by dynamic contrast-enhanced MRI. The location of the dentate line was assessed on MRI in 27 patients with upper-mid rectal cancer. Two observers independently evaluated the distance between the distal tumor edge and the MRI-defined dentate line in 54 patients with low rectal cancer, and the imaging and histological findings were compared. Results: The MRI-defined dentate line was 24.0 ± 3.8 mm above the anal verge in patients with upper-mid rectal cancer. The dentate line invasion status agreed with the histological findings in 49/54 (91%) patients (κ = 0.72 [95% CI 0.50-0.95]) for observer 1, and in 51/54 (94%) patients (κ = 0.83 [0.65-1.00]) for observer 2 in patients with low rectal cancer. Interobserver agreement was good (κ = 0.83 [0.65-1.00]). The MRI-derived distance between the distal tumor edge and the dentate line had significant correlation with the histological distance (r = 0.86 for reader 1 and 0.75 for observer 2). Conclusion: MRI demonstrates high accuracy in predicting dentate line invasion in low rectal cancer.
Description: 博士(医学)・甲第748号・令和2年6月30日
© Japan Radiological Society 2020
© 2020 Springer Nature Switzerland AG. Part of Springer Nature.
This is a post-peer-review, pre-copyedit version of an article published in Japanese journal of radiology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11604-020-00933-5.
発行元が定める登録猶予期間終了の後、本文を登録予定(2021.06)
URI: http://hdl.handle.net/10564/3755
ISSN: 18671071
Academic Degrees and number: 24601A748
Degree-granting date: 2020-06-30
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2020年度

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