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Vol.48 No.3 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/374

Title: 転移性骨腫瘍で発症した細小肝細胞癌の1例
Other Titles: A CASE OF SMALL HEPATOCELLULAR CARCINOMA DETECTED BY BONE METASTATIC LESION
Authors: 西本, 和央
西野, 俊彦
椎木, 英夫
金内, 雅夫
土肥, 和紘
夏目, 由美子
廣橋, 伸治
市島, 國雄
Keywords: PIVKA-Ⅱ
hepatocellular carcinoma
bone metastasis
Issue Date: 30-Jun-1997
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.48 No.3 p.178-182
Abstract: A 68-year-old male was referred to our clinic because of pain of left tuber of ischium. Bone roentgenogram of pelvis showed destructive change of the left pubic bone. Laboratory data on admission showed positive anti-HCV antibody, elevation of protein induced by vitamin K antagonists-Ⅱ (PIVKA-Ⅱ), elevation of GOT and GPT, depression of cholinesterase, and hypergammaglobulinemia. Biopsy of the pubic bone suggested metastasis of hepatocellular carcinoma, whereas no masses were detected by computerized tomographic (CT) scan and ultrasound (US) scan of liver. He underwent 60 Gly of irradiation for bone lesion. Three months later, PIVKA-Ⅱ was increased and US scan of liver showed hypoechoic masses that were clearly enhanced on both CT and MRI. This is an extremely rare case with hepatocellular carcinoma that manifested with bone metastasis and elevation of PIVKA-Ⅱ before detectable liver mass.
URI: http://hdl.handle.net/10564/374
ISSN: 04695550
13450069
Appears in Collections:Vol.48 No.3

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