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Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3673

Title: Clinical profile of SUNCT/SUNA in Japan: A clinic-based study.
Other Titles: 日本におけるSUNCT/SUNAの臨床像 : クリニックベースの研究
Authors: Kikui, Shoji
Miyahara, Junichi
Sugiyama, Hanako
Yamakawa, Kentaro
Kashiwaya, Yoshihiro
Ishizaki, Kumiko
Danno, Daisuke
Takeshima, Takao
Keywords: headache disorders
trigeminal neuralgia
Issue Date: 20-Feb-2019
Publisher: SAGE Publications Ltd.
Citation: Cephalalgia Reports Vol.2 p.1-6 (2019 Feb 20)
Abstract: Objectives:This study aimed to report the clinical profiles of patients with short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT)/short-lasting unilateral neuralgiform headache attacks with cranial autonomic (SUNA) in a Japanese population by surveying those enrolled at a regional headache center in Japan.Methods:In this consecutive case series study, the clinical characteristics of patients with SUNCT (eight men, three women; mean age: 59.5 ± 20.5 years) and SUNA (five men, four women; mean age: 51.3 ± 18.4 years) who visited Tominaga Hospital from February 2011 to January 2017 were examined. Headaches were diagnosed according to the International Classification of Headache Disorders, Third edition (ICHD-3) guidelines.Results:Brief clusters of separate attacks were reported by all patients. The mean duration of attacks was 91.9 ± 87.9 s. Ipsilateral rhinorrhea was observed in 9 of 20 (45.0%) cases and facial sweating was observed in 1 of 20 (5.0%) cases. An eminent response to lamotrigine was observed in 9 of 9 (100%) patients; however, adverse events were only reported in 2 of 9 (22.2%) cases. An intravenous infusion of lidocaine was demonstrated to be completely successful for short-term prevention in 5 of 6 (83.3%) SUNCT cases.Conclusions:Lamotrigine can successfully treat most patients, and intravenous lidocaine is useful for the short-term preventive therapy of severe recalcitrant attacks in Japanese patients with SUNCT/SUNA.
Description: 博士(医学)・乙第1437号・令和元年9月27日
Copyright © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
URI: http://hdl.handle.net/10564/3673
ISSN: 25158163
Academic Degrees and number: 24601B1437
Degree-granting date: 2019-09-27
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2019年度

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