アルコール摂取後に高度の高脂血症を呈したChurg-Strauss症候群による心筋炎の1例

Abstract

We report a 46-year-old man with myocarditis due to Churg-Strauss syndrome, who was admitted to our hospital because of marked hyperlipidemia and liver dysfunction. He had been an outpatient because of the impaired cardiac function after myocarditis due to Churg-Strauss syndrome. He had drunk alcohol 200mg/day for 3 months before admission. His serum at the outpatient clinic was markedly hemolytic and chylous. The serum bilirubin level was 2.2 mg/dl, of which direct bilirubin was 1.1 mg/dl. The serum cholesterol level was 801 mg/dl, and the triglyceride level was 3,564 mg/dl. Macrocytic hyperchromic anemia was revealed. These abnormalities improved rapidly after admission. The cause of his severe hyperlipidemia was attributed to the complication of Zieve's syndrome, because the triad of the syndrome, jaundice, hyperlipidemia and hemolytic anemia, were present after the alcohol abuse. Furthermore, the hyperlipidemia was thought to be enhanced by the adrenocorticosteroid, which had been prescribed for myocarditis due to Churg-Strauss syndrome.