DSpace About DSpace Software 日本語

01 奈良県立医科大学 >
011 医学部 >
0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.48 No.2 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/356

Title: 頭部外傷後に発症したと考えられるadrenocorticotropic hormone(ACTH)単独欠損症の1例
Authors: 藤本, 伸一
上村, 史朗
橋本, 俊雄
土肥, 和鉱
Keywords: isolated ACTH deficiency
head injury
Issue Date: 30-Apr-1997
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.48 No.2 p.65-70
Abstract: A 52-year-old male was admitted to our hospital with the complaints of general malaise, pretibial edema, speech disturbance, difficulty of grasping, hip joint pain, and calf myalgia. He had fallen from the roof of his house and had skull fracture and brain injury at 30 years old. After the accident, he had manifested general malaise and pretibial edema several times a year. Laboratory data on admission revealed high antidiuretic hormone secretion (0.9 pg/ml), in spite of low plasma sodium level (120 mEq/1) and low plasma osmotic pressure (255 mOsm/kg・H₂O). Then he was diagnosed as having syndrome of inappropriate secretion of antidiuretic hormone (SIADH). Further endoclinological investigation revealed isolated adrenocorticotropic hormone (ACTH) deficiency low plasma cortisol. Intravenous administration of ACTH raised plasma cortisol level, and insulim-induced hypoglycemia made blunted response of ACTH. These finding's confirmed that he had isolated ACTH deficiency. The electroencephalogram revealed diffuse slow wave, and brain MRI showed normal pituitary gland. The electromyogram revealed the neurological pattern on right deltoid muscle, biceps brachii muscle, and triceps brachii muscle, and myogenic pattern on abductor digiti minimi muscle. Corticosteroid replacement therapy improved both clinical symptoms and manifestation of SIADH. This is a rare case of isolated ACTH deficiency with various kind of symptoms which occurred after head injury.
URI: http://hdl.handle.net/10564/356
ISSN: 04695550
Appears in Collections:Vol.48 No.2

Files in This Item:

File Description SizeFormat
65-70p.頭部外傷後に発症したと考えられるadrenocorticotropic_hormone(ACTH)単独欠損症の1例.pdf1.22 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback