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Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3329

Title: Association of Visual Acuity and Cognitive Impairment in Older Individuals: Fujiwara-kyo Eye Study.
Other Titles: 高齢者における視機能と認知機能障害の関連 : 藤原京アイスタディより
Authors: Mine, Masashi
Miyata, Kimie
Morikawa, Masayuki
Nishi, Tomo
Okamoto, Nozomi
Kawasaki, Ryo
Yamashita, Hidetoshi
Kurumatani, Norio
Ogata, Nahoko
Keywords: aging
neuroscience
regeneration
Issue Date: 1-Aug-2016
Publisher: Mary Ann Liebert, Inc.
Citation: BioResearch open access Vol.5 No.1 p.228-234 (2016 Aug)
Abstract: Both visual impairment and cognitive impairment are essential factors that determine the quality of life in the aged population. The aim of this study was to determine if a correlation existed between visual acuity and cognitive impairment in an elderly Japanese population. The Fujiwara-kyo Eye Study was a cross-sectional study of individuals aged ≥68 years who lived in Nara Prefecture of Japan. Participants underwent ophthalmological examinations and cognitive function test. A mild visual impairment was defined as having a best corrected visual acuity (BCVA) >0.2 logarithm of the minimum angle of resolution (logMAR) units in the better eye. Cognitive impairment was defined as having a Mini-Mental State Examination (MMSE) score of ≤23 points. A total to 2818 individuals completed the examinations. The mean age of the participants was 76.3 ± 4.8 years (mean ± standard deviation). The mean BCVA of the better eye was -0.02 ± 0.13 logMAR units and 6.6% subjects were classified as being mildly visually impaired. The mean MMSE score was 27.3 ± 2.3 and 5.7% subjects were classified as being cognitively impaired. The proportion of subjects with cognitive or moderate visual impairment increased with age, and there was a significant correlation between the visual acuity and MMSE score (r = -0.10, p < 0.0001). Subjects with mild visual impairments had 2.4 times higher odds of having cognitive impairment than those without visual impairment (odds ratio 2.4, 95% confidence interval, 1.5-3.8, p < 0.001) after adjusting for age, sex, and length of education. We conclude that it may be important to maintain good visual acuity to reduce the risk of having cognitive impairment.
Description: 博士(医学)・乙第1396号・平成29年3月15日
© Masashi Mine et al. 2016; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
URI: http://hdl.handle.net/10564/3329
ISSN: 21647860
Academic Degrees and number: 24601B1396
Degree-granting date: 2017-03-15
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2016年度

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