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Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/3108

Title: Correlation between the ABC classification and radiological findings for assessing gastric cancer risk.
Other Titles: 胃がんリスク評価におけるABC分類とX線所見の関連性について
Authors: Itoh, Takahiro
Saito, Miho
Marugami, Nagaaki
Hirai, Toshiko
Marugami, Aki
Takahama, Junko
Tanaka, Toshihiro
Kichikawa, Kimihiko
Keywords: Helicobacter pylori
ABC classification
Gastric cancer
Radiological finding
Issue Date: Oct-2015
Publisher: Japan Radiological Society / Springer Japan
Citation: Japanese journal of radiology Vol.33 No.10 p.636-644 (2015.10)
Abstract: PURPOSE:To investigate the correlation between ABC risk assessment and radiological findings of gastric mucosa and to propose an improved method for gastric cancer screening. MATERIALS AND METHODS:We evaluated 318 participants with Helicobacter pylori (Hp) antibody titers, serum pepsinogen (PG) and upper GI radiography and then classified them into three groups: A, double-negative; B, Hp-positive, PG-negative; C, PG-positive. Group A was subclassified as: A-1, Hp antibody titer <3.0 U/ml; A-2, Hp antibody titer ≥3.0 U/ml. Results for group A and non-A (B or C) participants and radiological findings of gastric mucosa (fold and area gastricae) were analyzed retrospectively. RESULTS:Radiological findings differed significantly between the 207 A-1 and 98 non-A group. Odds ratios were 17.72 for fold distribution, 10.63 for fold thickness, 6.10 for fold characteristics, and 10.62 for area gastricae. Presence of ≥2 risk factors offered 90.3 % sensitivity, 94.7 % specificity, and 93.3 % accuracy. Nine (69.2 %) of the 13 A-2 group participants and 11 (5.3 %) A-1 group participants had a risk for gastric cancer according to radiological findings. CONCLUSION:A good correlation exists between ABC classifications and radiological findings for gastric cancer risk, but some discrepant cases exist. We recommend both methods as screening for gastric cancer.
Description: 博士(医学)・乙第1370号・平成27年11月27日
© Japan Radiological Society 2015
© Springer-Verlag Berlin Heidelberg 2015
The final publication is available at Springer via http://dx.doi.org/10.1007/s11604-015-0469-3
URI: http://hdl.handle.net/10564/3108
ISSN: 18671071
Academic Degrees and number: 24601B1370
Degree-granting date: 2015-11-27
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2015年度

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01_乙1370本文の要旨.pdf乙1370本文の要旨215.41 kBAdobe PDFView/Open
02_乙1370審査要旨.pdf乙1370審査要旨399.95 kBAdobe PDFView/Open
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04_乙1370Figure_1-5.pdf乙1370Figure 1-5812.45 kBAdobe PDFView/Open
05_乙1370Table1_1-5.pdf乙1370Table1 1-5283.35 kBAdobe PDFView/Open

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