甲状腺製剤(チラージンS)が奏功した神経性食息不振症の一例

Abstract

A 10 year-old girl, diagnosed as anorexia nervosa (AN), had suffered a loss of weight from 33kg to 23kg, and school-phobia during about 10 months. She showed low T3 syndrome at the laboratory examination : T3 0.4ng/ml, T4 4.7μg/ml, TSH 1.2μU/ml and low response of TSH to TRH dose test. Since some psychological treatments had not been effective for her symptoms, we administered a small amount of T4 product in order to improve the low T3 syndrome, which could be one component of the vicious circle on the AN. In this case, the T4 was rather effective : she became cheerful and regained her appetite, gaining 4kg in weight ; laboratory data improved as well. These results suggest that T4 product could be one of the appropriate medicines to treat patients with AN accompanied by low T3 syndrome.