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Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/2707

Title: Sentinel Lymph Node Detection in Patients with Oral Cancer by MR Lymphography using Superparamagnetic Iron Oxide.
Other Titles: 超常磁性体を用いたMRリンフォグラフィーによる口腔癌患者のセンチネルリンパ節同定
Authors: Uemura, Hirokazu
Ota, Ichiro
Fujii, Takashi
Suzuki, Motoyuki
Sakai, Mio
Nakanishi, Katsuyuki
Tomita, Yasuhiko
Noguchi, Atsushi
Hosoi, Hiroshi
Yoshino, Kunitoshi
Keywords: Head and neck cancer
sentinel lymph node
superparamagnetic iron oxide
MR lymphography
Issue Date: Jan-2013
Publisher: Bentham Open
Citation: Open Otorhinolaryngology Journal Vol.7 p.14-18
Abstract: The purpose of this study was to examine the feasibility of interstitial MR lymphography using Superparamagnetic Iron Oxide (SPIO) to detect sentinel lymph nodes (SLNs) in head and neck cancer. For two patients with cT2N0 squamous cell carcinoma of the tongue, the submucosal injection of SPIO as well as sentinel lymph node navigation surgery (SLNNS) was performed before undergoing surgical treatment. SPIO was used for MR lymphography and Tc-99m phytate for SPECT. We compared the images by both modalities. Berlin blue stain was also performed postoperatively if SLNs had the uptake of SPIO. The lymph nodes with MR signal attenuation and those with hot spots were probed to be anatomically identical. All the lymph nodes detected as a SLN by a gamma-probe contained the blue granules from SPIO. These data suggest that SPIO can be a novel tracer for performing SLNNS and SLN biopsy in oral cancer patients with cN0 neck.
Description: 博士(医学)・甲622号・平成26年3月17日
URI: http://hdl.handle.net/10564/2707
ISSN: 18744281
Academic Degrees and number: 24601A622
Degree-granting date: 2014-03-17
Degree name: 博士(医学)
Degree-granting institutions: 奈良県立医科大学
Appears in Collections:2013年度

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