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Vol.40 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/2314

Title: Amphotericin Bの大量経口投与と吸入による深部真菌症の予防の試み : 造血器悪性腫瘍患者の剖検例5例での検討
Other Titles: PROPHYLAXIS OF DEEP MYCOSIS BY LARGE DOSES OF ORAL AMPHOTERICIN B AND INHALATION OF AEROSOLIZED FORM : AUTOPSY EXAMINATIONS OF FIVE PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
Authors: 小嶌, 興二
西川, 潔
下山, 丈人
水本, 保子
成田, 亘啓
Keywords: Amphotericin B
経口投与
吸入投与
真菌症
顆粒球減少症
病理解剖
Issue Date: 28-Feb-1989
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.40 No.1 p.39-45
Abstract: Autopsy examinations were conducted in five patients with hematological malignancies, especially in search of fungal infections. All of them had several risk factors includind prolonged granulocytopenia, treatment with broad-spectrum antibiotics, anticancer therapy, insertion of central venous catheters and so on. They all received prophylactically large doses of oral amphotericin B suspension (2.4 g/d) as well as inhalation of aerosolized amphotericin B, except for one patient who received only oral therapy, but none of them received intravenous administration. Results of postmortem examinations were : 1) immediate causes of death, without exception, were nonmycotic infections, 2) None of the five patients had signs of fungal colonization throughout the digestive tract or in deep organs.
URI: http://hdl.handle.net/10564/2314
ISSN: 04695550
13450069
Appears in Collections:Vol.40 No.1

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