エロソール吸入シンチグラフィにおける沈着パターンの検討：第一報 各種肺疾患における沈着パターンの解析ならびに肺機能との対比

Abstract

The deposition patterns of aerosol inhalation scintigraphies and lung function tests were studied in 102 cases ; 64 cases of obstructive pulmonary diseases (19 pulmonary emphysema, 27 diffuse panbronchiolitis, 18 chronic bronchitis) and 38 restrictive pulmonary diseases (15 idiopathic interstitial pneumonia, 16 pulmonary asbestosis, 7 interstitial pneumonia due to collagen vascular disease). The deposition patterns were classified into 5 patterns (Type A : normal homogenous distribution ; Type B : mildly unhomogenous distribution ; Type C : severely unhomogenous distribution mingled with hot spots ; Type D : non-hilar hot spots ; and Type E : hilar hot spots). The results were as follows ; 1) The deposition patterns of restrictive pulmonary diseases were markedly abnormal as well as obstructive pulmonary diseases. 2) The deposition patterns showed mainly Types C, D and E in obstructve pulmonary diseases, Type B in restrictive pulmonary diseases. The deposition patterns showed mainly Type E in pulmonary emphysema, Types C and D in diffuse panbronchiolitis, Types A, B and C in chronic bronchitis, Type B in idiopathic interstitial pneumonia interstitial pneumonia due to collagen vascular disease, Types B and C in pulmonary asbestosis. 3) The deposition patterns correlated well with % FEV₁.₀ which was a good indicator of the severity of obstructive pulmonary diseases and restrictive pulmonary diseases. Furthermore, the mean % FEV₁.₀ in obstructve pulmonary diseases was nearly equal to the mean % FEV₁.₀ in restrictve pulmonary diseases in each type of the deposition patterns. I concluded that aerosol scintigraphy was very useful to represent not only regional lung function but also total lung function.