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01121 Journal of Nara Medical Association >
Vol.54 No.5-6 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/209

Title: 免疫組織染色を用いたα2-HS glycoproteinの臓器分布
Authors: 吉田, 裕慈
高橋, 幸博
川口, 千晴
中島, 充
吉岡, 章
Keywords: α2-HS glycoprotein
immunohistological staining
bone metabolism
Issue Date: 31-Dec-2003
Publisher: 奈良医学会
Citation: Journal of Nara Medical Association Vol.54 No.5-6 p.283-288
Abstract: Alpha2-HS glycoprotein (α2-HS) is a plasma glycoprotein with a molecular weight of 49 kDa and is synthesized in the liver. Although it is generally accepted that α2-HS is involved in bone metabolism, its physiological functions have not been fully elucidated. Hence, in order to clarify the function of α2-HS, its distribution in the body was investigated by immunohistological staining using tissue samples obtained by autopsy. The results showed that, as previously known, α2-HS existed abundantly in the liver and bones, and was also detected in organs such as heart, pancreas, kidney, small intestine and brain, but not in the lung, spleen or adrenal gland. The results of the present study clarify that α2-HS exists in many organs besides the bones, suggesting that α2-HS is a multi-fUnction protein involved not only in bone metabolism, but also in other physiological reactions.
URI: http://hdl.handle.net/10564/209
ISSN: 13450069
Appears in Collections:Vol.54 No.5-6

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