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01121 Journal of Nara Medical Association >
Vol.54 No.5-6 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/209
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Title: | 免疫組織染色を用いたα2-HS glycoproteinの臓器分布 |
Other Titles: | SYSTEMIC DISTRIBUTION OF α2-HS GLYCOPROTEIN BY IMMUNOHISTOLOGICAL STAINING |
Authors: | 吉田, 裕慈 高橋, 幸博 川口, 千晴 中島, 充 吉岡, 章 |
Keywords: | α2-HS glycoprotein immunohistological staining bone metabolism autopsy |
Issue Date: | 31-Dec-2003 |
Publisher: | 奈良医学会 奈良県立医科大学 |
Citation: | Journal of Nara Medical Association Vol.54 No.5-6 p.283-288 |
Abstract: | Alpha2-HS glycoprotein (α2-HS) is a plasma glycoprotein with a molecular
weight of 49 kDa and is synthesized in the liver. Although it is generally accepted that
α2-HS is involved in bone metabolism, its physiological functions have not been fully
elucidated. Hence, in order to clarify the function of α2-HS, its distribution in the body
was investigated by immunohistological staining using tissue samples obtained by
autopsy. The results showed that, as previously known, α2-HS existed abundantly in the
liver and bones, and was also detected in organs such as heart, pancreas, kidney, small
intestine and brain, but not in the lung, spleen or adrenal gland. The results of the
present study clarify that α2-HS exists in many organs besides the bones, suggesting
that α2-HS is a multi-fUnction protein involved not only in bone metabolism, but also in
other physiological reactions. |
URI: | http://hdl.handle.net/10564/209 |
ISSN: | 13450069 |
Appears in Collections: | Vol.54 No.5-6
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