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01121 Journal of Nara Medical Association >
Vol.41 No.6 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/2023
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Title: | 難治性腹水に選択的β₁-blockerが有効であったBudd-Chiari症候群の一例 |
Other Titles: | A CASE OF BUDD-CHIARI SYNDROME WITH REFRACTORY ASCITES WHICH RESPONDED TO SELECTIVE β₁-BLOCKER |
Authors: | 小嶌, 秀之 松村, 雅彦 菊川, 政次 高木, 正博 森田, 倫史 福井, 博 辻井, 正 |
Keywords: | Budd-Chiari syndrome refractory ascites selective β₁-blocker portal hypertension severe liver disturbance |
Issue Date: | 31-Dec-1990 |
Publisher: | 奈良医学会 |
Citation: | 奈良医学雑誌 Vol.41 No.6 p.675-678 |
Abstract: | A 36-year-old female with Budd-Chiari syndrome who had refractory ascites and hepatic failure is reported. Sodium restriction, infusion of albumin, and administration of various diuretics were not effective. Because the effect of β-blocker on
portal hypertension had been reported and portal hypertension was considered to be one of the main causes for ascites in this case, selective β₁-blocker metoprolol (80 mg/day) was added to diuretics. As a result, her ascites rapidly disappeared. Selective β₁-blocker has no adverse effect on hepatic blood flow, and therefore was considered to be relatively safe for patients with severe liver disturbance. Selective β₁- blocker seems to be promising in the treatment of refractory ascites, for which portal hypertension has a major pathogenetic role. |
URI: | http://hdl.handle.net/10564/2023 |
ISSN: | 04695550 13450069 |
Appears in Collections: | Vol.41 No.6
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