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Vol.41 No.6 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/2023

Title: 難治性腹水に選択的β₁-blockerが有効であったBudd-Chiari症候群の一例
Other Titles: A CASE OF BUDD-CHIARI SYNDROME WITH REFRACTORY ASCITES WHICH RESPONDED TO SELECTIVE β₁-BLOCKER
Authors: 小嶌, 秀之
松村, 雅彦
菊川, 政次
高木, 正博
森田, 倫史
福井, 博
辻井, 正
Keywords: Budd-Chiari syndrome
refractory ascites
selective β₁-blocker
portal hypertension
severe liver disturbance
Issue Date: 31-Dec-1990
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.41 No.6 p.675-678
Abstract: A 36-year-old female with Budd-Chiari syndrome who had refractory ascites and hepatic failure is reported. Sodium restriction, infusion of albumin, and administration of various diuretics were not effective. Because the effect of β-blocker on portal hypertension had been reported and portal hypertension was considered to be one of the main causes for ascites in this case, selective β₁-blocker metoprolol (80 mg/day) was added to diuretics. As a result, her ascites rapidly disappeared. Selective β₁-blocker has no adverse effect on hepatic blood flow, and therefore was considered to be relatively safe for patients with severe liver disturbance. Selective β₁- blocker seems to be promising in the treatment of refractory ascites, for which portal hypertension has a major pathogenetic role.
URI: http://hdl.handle.net/10564/2023
ISSN: 04695550
13450069
Appears in Collections:Vol.41 No.6

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