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Vol.42 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/2011

Title: A SCINTIGRAPHIC STUDY OF MASS PERISTALSIS IN HUMAN COLON
Authors: Yasuda, Shinji
Murakami, Koji
Fujii, Hisao
Yamamoto, Katsuhiko
Sado, Saburo
Yamamoto, Masatoshi
Nakagawa, Masayuki
Watanabe, Iwao
Yoshikawa, Syusaku
Nakano, Hiroshige
Keywords: mass peristalsis
scintigraphy
colonofiberscopy
Issue Date: 28-Feb-1991
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.42 No.1 p.88-95
Abstract: Although many attempts have been made to study human colonic motility, the colonic transit is still poorly understood. Both spontaneous and neostigmine-induced peristalsis of the colon were studied with scintigraphy. A polythene tube was inserted into the cecum through a colonofiberscope. 37 MBq of ⁹⁹ᵐTc-DTPA and 75 ml of saline were instilled and dynamic scan was begun. Eight healthy volunteers were examined by the method above mentioned. The sampling time was set at fifteen seconds in six persons and three seconds in the rest. 0.5 mg of neostigmine was injected intravenously to stimulate the paristalsis when no peristalsis occurred within thirty minutes after the study was begun. Dynamic scanning was performed for sixty to ninety minutes. This scintigraphic study revealed that the spontaneous and induced peristalsis were almost identical on colonogram. ⁹⁹ᵐTc-DTPA solution was propelled from the cecum and ascending colon to the sigmoid colon or the rectum for about fifteen seconds during mass peristalsis. Colonogram (time-activity curve) enables us to analyze mass peristalsis easily and more objectively than colonoscintigram. The spontaneous and neostigmine-induced peristalsis seemed to be almost identical in all but one of eight subjects.
URI: http://hdl.handle.net/10564/2011
ISSN: 04695550
13450069
Appears in Collections:Vol.42 No.1

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