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Vol.42 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/2007

Title: TUMOR MARKERS IN BONE MARROW IN PATIENTS WITH PROSTATIC CANCER
Authors: Iwai, Akio
Ozono, Seiichiro
Tanaka, Yozo
Nagayoshi, Junichi
Hirayama, Akihide
Kumon, Toshihiko
Joko, Masanori
Hirata, Naoya
Yoshikawa, Motoyoshi
Tabata, Shoichi
Uemura, Hirotsugu
Moriya, Akira
Kaneko, Yoshiteru
Okamoto, Shinji
Hirao, Yoshihiko
Okajima, Eigoro
Keywords: tumor markers
bone marrow
prostatic cancer
Issue Date: 28-Feb-1991
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.42 No.1 p.62-66
Abstract: We compared prostatic specific acid phosphatase (PAP), prostatic specific antigen (PA) and γ-seminoprotein (γ-SM) levels between bone marrow and serum for the purpose of assessing of the usefulness of these tumor markers in early detection of bone metastasis in cases with prostatic cancer. Thirty-three patients were entered into this study. Of the patients, 20 had prostatic cancer including 11 with bone metastasis, and 13 patients had benign prostatic hypertrophy (BPH) served as controls. It seemed unlikely that bone marrow PAP, PA and γ-SM are more useful than their serum levels for detection of bone metastasis of prostatic cancer. Because correlation between bone marrow and serum levels of each marker was observed not only in cases with prostate cancer accompanied by bone metastasis but also in metastasis-free prostatic cancer and BPH cases, it seems likely that PAP, PA and γ-SM in bone marrow circulate from peripheral blood rather than from bone metastasis of prostatic cancer.
URI: http://hdl.handle.net/10564/2007
ISSN: 04695550
13450069
Appears in Collections:Vol.42 No.1

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