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01121 Journal of Nara Medical Association >
Vol.42 No.3 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/1984

Title: 機能性甲状腺癌の一例
Authors: 西山, 利正
岡本, 新悟
富永, 謙太郎
細川, 彰子
梅本, 典江
泉, 由紀子
福井, 博
辻井, 正
田中, 治
松永, 喬
日浅, 義雄
Keywords: functioning thyroid carcinoma
follicular carcinoma
Issue Date: 30-Jun-1991
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.42 No.3 p.231-239
Abstract: A 62-year-old woman with large tumor of the thyroid manifesting thyrotoxicosis is presented. Thyroid function tests showed a slight hyperthyroidism. Radiolabelled iodine accumulated in some parts of the tumor and the others were cold. Triiodothyronin (l-T_3) administration showed non-suppression of the hot pattern. Moreover the blood thyroxin level was not lowered following the suppression of thyrotropin (TSH) induced by l-T_3 administration. A total tumorectomy was performed and the pathological examination showed various degrees of follicular carcinoma. Histological findings were compared to the radiolabelled iodine uptake by mapping of thyroid scintigram. The most highly accumulated area of radiolabelled iodine consisted of smaller follicles with coloid. However, the unaccumulated areas consisited of cancer cells simulated in fetal thyroid or solid and trabecular patterns. This clinical evidence indicates that thyrotoxicosis in this case is caused by the excessive secretion of thyroid hormones from which were produced the cancer cells of highly accumulated area of radiolabelled iodine.
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URI: http://hdl.handle.net/10564/1984
ISSN: 04695550
Appears in Collections:Vol.42 No.3

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