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Vol.42 No.4 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/1972

Title: 脳出血後に発見された選択的低アルドステロン症の1例
Other Titles: A CASE OF SELECTIVE HYPOALDOSTERONISM DIAGNOSED AFTER CEREBRAL HEMORRHAGE
Authors: 松田, 吉史
野中, 秀郎
平田, 英二
佐々木, 嘉彦
伴, 圭一郎
上田, 一也
小川, 修二
林, 勝文
清水, 和男
有吉, 浄治
石川, 兵衞
Keywords: selective hypoaldosteronism
PRA
plasma aldosterone
hyponatremia
hyperkalemia
Issue Date: 31-Aug-1991
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.42 No.4 p.319-326
Abstract: A 54 year-old male who had suffered from an attack of cerebral hemorrhage five months before was admitted because of increasing dizziness and fatigue. Laboratory examinations on admission revealed both hyponatremia and hyperkalemia. Despite the elevation of plasma renin activity (PRA), plasma aldosterone level was markedly low. Both basal plasma cortisol level and urinary 17-OHCS excretion rate were normal. While cortisol showed a normal response to rapid ACTH infusion test, plasma aldosterone showed no or very low response to each of the endocrinological tests carried out (rapid ACTH infusion test, angiotensin Ⅱ infusion test and furosemide two-hour standing test). However, PRA showed a marked increase in response to furosemide two-hour standing test. On the basis of these findings, a diagnosis of selective hypoaldosteronism (Type Ⅰ) was entablished. The present disease was probably due to destruction of the zona glomerulosa of the adrenal cortex caused by some autoimmune mechanism.
URI: http://hdl.handle.net/10564/1972
ISSN: 04695550
13450069
Appears in Collections:Vol.42 No.4

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