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Vol.42 No.5 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/1953

Title: 原発性肺癌,肺動静脈瘻,肝動脈瘤および肝血管腫を合併したOsler-Rendu-Weber病の1剖検例
Other Titles: A RARE AUTOPSY CASE OF OSLER-RENDU-WEBER DISEASE COMPLICATED WITH PRIMARY LUNG CANCER, PULMONARY ARTERIOVENOUS FISTULA, HEPATIC ANEURYSMS AND HEPATIC HEMANGIOMAS
Authors: 塚本, 美奈
土肥, 和紘
南, 繁敏
加藤, 茂
坂口, 泰弘
藤井, 謙裕
籠島, 忠
石川, 兵衞
廣田, さち子
大沢, 政彦
青笹, 克之
Keywords: hepatic aneurysm
hepatic hemangioma
lung cancer
Osler-Rendu-Weber disease
pulmonary arteriovenous fistula
Issue Date: 31-Oct-1991
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.42 No.5 p.401-406
Abstract: A 63-year-old male was hospitalized because of nasal and gingival bleeding. Owing to characteristic small and red-to-violet telangiectatic lesions on his face, lips, oral, nasal mucosa, and finger tips, he was diagnosed as having Osler-Rendu-weber disease. Biopsy of the mucosa of his lower lip showed marked telangiectasia. After several months, we found association of primary pulmonary cancer, pulmonary arteriovenous fistulae, hepatic aneurysms and hepatic hemangiomas. After a few months, the patient died of disseminated intravascular coagulation. Autopsy and pathological examination, revealed primary large cell carcinoma of the lung, metastatic lesions in the brain and the liver, hepatic aneurysms and hepatic hemangiomas. Pulmonary arteriovenous fistulae are frequently complicated with this disease. To our knowledge, this is the first report on Osler-Rendu-Weber disease with primary lung cancer. Histopathologically, pulmonary arteriovenous fistulae were seen in the right lung and primary lung cancer was found in the left lung. The etiological relationship between the fistulae and the cancer was not recogized. It was suggested that the rapid metastasis to several organs could have been due to pulmonary arteriovenous fistulae.
URI: http://hdl.handle.net/10564/1953
ISSN: 04695550
13450069
Appears in Collections:Vol.42 No.5

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